Kevlishvili Group

Publications

2025

High-Throughput Discovery of Ferrocene Mechanophores with Enhanced Reactivity and Network Toughening
High-Throughput Discovery of Ferrocene Mechanophores with Enhanced Reactivity and Network Toughening
Kevlishvili Ilia, Jafer Vakil, Kastner David, Huang Xiao, Craig Stephen, Kulik Heather
ACS Central Science  ·  01 Aug 2025  ·  doi:10.1021/acscentsci.5c00707
The Role of the Unusual 2-Tyr-1-carboxylate Nonheme Iron Motif in the Mechanism of i N i , i N i -Dimethylformamidase
The Role of the Unusual 2-Tyr-1-carboxylate Nonheme Iron Motif in the Mechanism of N,N-Dimethylformamidase
David W. Kastner, Clorice R. Reinhardt, Husain Adamji, Terence S. Oscar-Okpala, Ilia Kevlishvili, Yuriy Román-Leshkov, Heather J. Kulik
ACS Catalysis  ·  14 Jul 2025  ·  doi:10.1021/acscatal.5c03335
Enabling Selective Mechanochemical Scission of Network Crosslinks by Exchanging Single Carbon Atoms for Silicon
Enabling Selective Mechanochemical Scission of Network Crosslinks by Exchanging Single Carbon Atoms for Silicon
Sophia J. Melvin, Yunxin Yao, Xiao Huang, Rowina C. Bell, Ryann E. Kemmerling, …, Ana Paula Kitos Vasconcelos, Alshakim Nelson, Heather J. Kulik, Stephen L. Craig, Rebekka S. Klausen
Journal of the American Chemical Society  ·  04 Feb 2025  ·  doi:10.1021/jacs.4c16323
Leveraging natural language processing to curate the tmCAT, tmPHOTO, tmBIO, and tmSCO datasets of functional transition metal complexes
Leveraging natural language processing to curate the tmCAT, tmPHOTO, tmBIO, and tmSCO datasets of functional transition metal complexes
Ilia Kevlishvili, Roland G. St. Michel, Aaron G. Garrison, Jacob W. Toney, Husain Adamji, Haojun Jia, Yuriy Román-Leshkov, Heather J. Kulik
Faraday Discussions  ·  01 Jan 2025  ·  doi:10.1039/D4FD00087K

2024

Force-Activated Spin-Crossover in Fe sup 2 sup and Co sup 2 sup Transition Metal Mechanophores
Force-Activated Spin-Crossover in Fe2+ and Co2+ Transition Metal Mechanophores
Xiao Huang, Ilia Kevlishvili, Stephen L. Craig, Heather J. Kulik
Inorganic Chemistry  ·  23 Dec 2024  ·  doi:10.1021/acs.inorgchem.4c04732
High-Throughput Discovery of Ferrocene Mechanophores with Enhanced Reactivity and Network Toughening
High-Throughput Discovery of Ferrocene Mechanophores with Enhanced Reactivity and Network Toughening
Heather Kulik, Ilia Kevlishvili, Jafer Vakil, David Kastner, Xiao Huang, Stephen Craig
Springer Science and Business Media LLC  ·  13 Sep 2024  ·  doi:10.21203/rs.3.rs-4882970/v1
Visible light mediated aza Paternò Büchi reaction of acyclic oximes and alkenes to azetidines
Visible light–mediated aza Paternò–Büchi reaction of acyclic oximes and alkenes to azetidines
Emily R. Wearing, Yu-Cheng Yeh, Gianmarco G. Terrones, Seren G. Parikh, Ilia Kevlishvili, Heather J. Kulik, Corinna S. Schindler
Science  ·  28 Jun 2024  ·  doi:10.1126/science.adj6771
Nested non-covalent interactions expand the functions of supramolecular polymer networks
Nested non-covalent interactions expand the functions of supramolecular polymer networks
David J. Lundberg, Christopher M. Brown, Eduard O. Bobylev, Nathan J. Oldenhuis, Yasmeen S. Alfaraj, Julia Zhao, Ilia Kevlishvili, Heather J. Kulik, Jeremiah A. Johnson
Nature Communications  ·  10 May 2024  ·  doi:10.1038/s41467-024-47666-x
Internal Catalysis in Dynamic Hydrogels with Associative Thioester Cross-Links
Internal Catalysis in Dynamic Hydrogels with Associative Thioester Cross-Links
Vivian Zhang, Carrie Ou, Ilia Kevlishvili, Christina M. Hemmingsen, Joseph V. Accardo, Heather J. Kulik, Julia A. Kalow
ACS Macro Letters  ·  03 May 2024  ·  doi:10.1021/acsmacrolett.4c00245
A Thermally Stable SO sub 2 sub -Releasing Mechanophore: Facile Activation, Single-Event Spectroscopy, and Molecular Dynamic Simulations
A Thermally Stable SO2-Releasing Mechanophore: Facile Activation, Single-Event Spectroscopy, and Molecular Dynamic Simulations
Yunyan Sun, William J. Neary, Xiao Huang, Tatiana B. Kouznetsova, Tetsu Ouchi, …, Kecheng Wang, Yingying Chen, Heather J. Kulik, Stephen L. Craig, Jeffrey S. Moore
Journal of the American Chemical Society  ·  06 Apr 2024  ·  doi:10.1021/jacs.4c02139
Self-Amplified HF Release and Polymer Deconstruction Cascades Triggered by Mechanical Force
Self-Amplified HF Release and Polymer Deconstruction Cascades Triggered by Mechanical Force
Yixin Hu, Liqi Wang, Ilia Kevlishvili, Shu Wang, Chun-Yu Chiou, Peyton Shieh, Yangju Lin, Heather J. Kulik, Jeremiah A. Johnson, Stephen L. Craig
Journal of the American Chemical Society  ·  30 Mar 2024  ·  doi:10.1021/jacs.4c01402
Visible-Light-Mediated Macrocyclization for the Formation of Azetine-Based Dimers
Visible-Light-Mediated Macrocyclization for the Formation of Azetine-Based Dimers
Cody H. Ng, Scott L. Kim, Ilia Kevlishvili, Gianmarco G. Terrones, Emily R. Wearing, Heather J. Kulik, Corinna S. Schindler
ACS Catalysis  ·  04 Mar 2024  ·  doi:10.1021/acscatal.3c04518
Large-scale comparison of Fe and Ru polyolefin C H activation catalysts
Large-scale comparison of Fe and Ru polyolefin C–H activation catalysts
Husain Adamji, Ilia Kevlishvili, Aditya Nandy, Yuriy Román-Leshkov, Heather J. Kulik
Journal of Catalysis  ·  01 Mar 2024  ·  doi:10.1016/j.jcat.2024.115361
Isomer-driven polymerization, depolymerization, and reconstruction
Isomer-driven polymerization, depolymerization, and reconstruction
Herbert Wakefield IV, Nicholas J. Fromel, Jennifer Jiang, Ilia Kevlishvili, Yunxin Yao, Stephen L. Craig, Heather J. Kulik, Rebekka S. Klausen
Polymer Chemistry  ·  01 Jan 2024  ·  doi:10.1039/D4PY01281J
Angle-strained sila-cycloalkynes
Angle-strained sila-cycloalkynes
Herbert Wakefield, Sophia J. Melvin, Jennifer Jiang, Ilia Kevlishvili, Maxime A. Siegler, Stephen L. Craig, Heather J. Kulik, Rebekka S. Klausen
Chemical Communications  ·  01 Jan 2024  ·  doi:10.1039/D4CC00439F

2023

Classification of Hemilabile Ligands Using Machine Learning
Classification of Hemilabile Ligands Using Machine Learning
Ilia Kevlishvili, Chenru Duan, Heather Kulik
American Chemical Society (ACS)  ·  18 Oct 2023  ·  doi:10.26434/chemrxiv-2023-66jqr-v2
Discovery of Hemilabile Ligands Using Machine Learning
Discovery of Hemilabile Ligands Using Machine Learning
Ilia Kevlishvili, Chenru Duan, Heather Kulik
American Chemical Society (ACS)  ·  05 Oct 2023  ·  doi:10.26434/chemrxiv-2023-66jqr

2022

Visible Light-Mediated 2 2 -Cycloadditions for the Formation of Macrocyclic Dimers
Visible Light-Mediated [2+2]-Cycloadditions for the Formation of Macrocyclic Dimers
Corinna Schindler, Cody Ng, Scott Kim, Ilia Kevlishvili, Gianmarco Terrones, Emily Wearing, Heather Kulik
American Chemical Society (ACS)  ·  21 Oct 2022  ·  doi:10.26434/chemrxiv-2022-h55mx
Endohedrally Functionalized Metal Organic Cage-Cross-Linked Polymer Gels as Modular Heterogeneous Catalysts
Endohedrally Functionalized Metal–Organic Cage-Cross-Linked Polymer Gels as Modular Heterogeneous Catalysts
Christopher M. Brown, David J. Lundberg, Jessica R. Lamb, Ilia Kevlishvili, Denise Kleinschmidt, Yasmeen S. Alfaraj, Heather J. Kulik, Maria Francesca Ottaviani, Nathan J. Oldenhuis, Jeremiah A. Johnson
Journal of the American Chemical Society  ·  12 Jul 2022  ·  doi:10.1021/jacs.2c04289
Highly efficient bromine capture and storage using N-containing porous organic cages
Highly efficient bromine capture and storage using N-containing porous organic cages
Sunggyu Lee, Ilia Kevlishvili, Heather J. Kulik, Hee-Tak Kim, Yongchul G. Chung, Dong-Yeun Koh
Journal of Materials Chemistry A  ·  01 Jan 2022  ·  doi:10.1039/D2TA05420E

2021

Capturing the Most Active State of a Palladium 0 Cross-Coupling Catalyst
Capturing the Most Active State of a Palladium(0) Cross-Coupling Catalyst
Sii Hong Lau, Liye Chen, Illia Kevlishvili, Katherine Davis, Peng Liu, Brad Carrow
American Chemical Society (ACS)  ·  13 Oct 2021  ·  doi:10.26434/chemrxiv-2021-477kn
Nickel-Catalyzed Radical Migratory Coupling Enables C-2 Arylation of Carbohydrates
Nickel-Catalyzed Radical Migratory Coupling Enables C-2 Arylation of Carbohydrates
Gaoyuan Zhao, Wang Yao, Ilia Kevlishvili, Jaclyn N. Mauro, Peng Liu, Ming-Yu Ngai
Journal of the American Chemical Society  ·  04 Jun 2021  ·  doi:10.1021/jacs.1c03563
Boron insertion into alkyl ether bonds via zinc nickel tandem catalysis
Boron insertion into alkyl ether bonds via zinc/nickel tandem catalysis
Hairong Lyu, Ilia Kevlishvili, Xuan Yu, Peng Liu, Guangbin Dong
Science  ·  09 Apr 2021  ·  doi:10.1126/science.abg5526
2π 2π Photocycloaddition of Enones to Single-Walled Carbon Nanotubes Creates Fluorescent Quantum Defects
[2π + 2π] Photocycloaddition of Enones to Single-Walled Carbon Nanotubes Creates Fluorescent Quantum Defects
Xiaoyun He, Ilia Kevlishvili, Katherina Murcek, Peng Liu, Alexander Star
ACS Nano  ·  09 Mar 2021  ·  doi:10.1021/acsnano.0c09583

2020

Anti-selective 3 2 Hetero annulation of non-conjugated alkenes via directed nucleopalladation
Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation
Hui-Qi Ni, Ilia Kevlishvili, Pranali G. Bedekar, Joyann S. Barber, Shouliang Yang, …, Andrew M. Romine, Hou-Xiang Lu, Indrawan J. McAlpine, Peng Liu, Keary M. Engle
Nature Communications  ·  22 Dec 2020  ·  doi:10.1038/s41467-020-20182-4
Highly Enantioselective Synthesis of Indazoles with a C3-Quaternary Chiral Center Using CuH Catalysis
Highly Enantioselective Synthesis of Indazoles with a C3-Quaternary Chiral Center Using CuH Catalysis
Yuxuan Ye, Ilia Kevlishvili, Sheng Feng, Peng Liu, Stephen L. Buchwald
Journal of the American Chemical Society  ·  14 May 2020  ·  doi:10.1021/jacs.0c04286

2019

The Thermal Rearrangement of an NHC Ligated 3 Benzoborepin to an NHC Boranorcaradiene
The Thermal Rearrangement of an NHC‐Ligated 3‐Benzoborepin to an NHC‐Boranorcaradiene
Masaki Shimoi, Ilia Kevlishvili, Takashi Watanabe, Katsuhiro Maeda, Steven J. Geib, Dennis P. Curran, Peng Liu, Tsuyoshi Taniguchi
Angewandte Chemie  ·  22 Nov 2019  ·  doi:10.1002/ange.201912234
The Thermal Rearrangement of an NHC Ligated 3 Benzoborepin to an NHC Boranorcaradiene
The Thermal Rearrangement of an NHC‐Ligated 3‐Benzoborepin to an NHC‐Boranorcaradiene
Masaki Shimoi, Ilia Kevlishvili, Takashi Watanabe, Katsuhiro Maeda, Steven J. Geib, Dennis P. Curran, Peng Liu, Tsuyoshi Taniguchi
Angewandte Chemie International Edition  ·  22 Nov 2019  ·  doi:10.1002/anie.201912234
A Short Synthesis of Delavatine A Unveils New Insights into Site-Selective Cross-Coupling of 3,5-Dibromo-2-pyrone
A Short Synthesis of Delavatine A Unveils New Insights into Site-Selective Cross-Coupling of 3,5-Dibromo-2-pyrone
Vignesh Palani, Cedric L. Hugelshofer, Ilia Kevlishvili, Peng Liu, Richmond Sarpong
Journal of the American Chemical Society  ·  15 Jan 2019  ·  doi:10.1021/jacs.8b13012

2018

Mechanistically Guided Design of Ligands That Significantly Improve the Efficiency of CuH-Catalyzed Hydroamination Reactions
Mechanistically Guided Design of Ligands That Significantly Improve the Efficiency of CuH-Catalyzed Hydroamination Reactions
Andy A. Thomas, Klaus Speck, Ilia Kevlishvili, Zhaohong Lu, Peng Liu, Stephen L. Buchwald
Journal of the American Chemical Society  ·  23 Sep 2018  ·  doi:10.1021/jacs.8b09565

2017

Glycosyl Cross-Coupling of Anomeric Nucleophiles: Scope, Mechanism, and Applications in the Synthesis of Aryl i C i -Glycosides
Glycosyl Cross-Coupling of Anomeric Nucleophiles: Scope, Mechanism, and Applications in the Synthesis of Aryl C-Glycosides
Feng Zhu, Jacob Rodriguez, Tianyi Yang, Ilia Kevlishvili, Eric Miller, Duk Yi, Sloane O’Neill, Michael J. Rourke, Peng Liu, Maciej A. Walczak
Journal of the American Chemical Society  ·  30 Nov 2017  ·  doi:10.1021/jacs.7b08707
Improved conditions for a direct and regioselective synthesis of 8-carboxyethyl-7-deazaguanine
Improved conditions for a direct and regioselective synthesis of 8-carboxyethyl-7-deazaguanine
Jeff M. Pruet, Ilia Kevlishvili
Tetrahedron Letters  ·  01 Apr 2017  ·  doi:10.1016/j.tetlet.2017.03.055